According to the study published by Sciencedaily, OLE helps microglia surround and contain beta-amyloid plaques, reducing ...

A team has identified an experimental molecule capable of "reprogramming" the brain's immune cells to restore part of their protective function against Alzheimer's disease. The study, published in the ...

Researchers have successfully demonstrated how astroglia—cells that support the functioning of the brain—can be reprogrammed into cells resembling interneurons. The research, published in Science ...

Promising mouse studies and billions of dollars in funding are stoking excitement. But we’ve been here before.

When a neuron ages, it loses synaptic connections with other neurons, it is less able to transmit nerve impulses, and its metabolism is also altered. This process of neuronal ageing — inevitable with ...

Age-related memory decline and neurodegenerative diseases like Alzheimer's are often thought of as irreversible. But the brain is not static; neurons continually adjust the strength of their ...

The lab of Filippo Veglia, Ph.D., at The Wistar Institute has discovered a previously unknown mechanism for how aggressive brain cancers reprogram immune system cells from fighting cancer to enabling ...

A mechanism underlying neutrophil reprogramming in brain cancers has been uncovered, illuminating potential therapeutic targets to stop their pro-cancer effect. Tumor-infiltrating neutrophils are ...

A newly identified molecule called OLE helped restore the brain’s immune cells to a more protective state in Alzheimer’s ...